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KMID : 0361019980410091133
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Korean Journal of Otolaryngology - Head and Neck Surgery
1998 Volume.41 No. 9 p.1133 ~ p.1136
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Ultrastructiural Changes of Mucous Blanket in Chronic Ethmoiditis
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이승훈/Seung Hoon Lee
박찬/김우정/임재신/정학현/Chan Park/Woo Jeong Kim/Jae Shin Lim/Hak Hyun Jung
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Abstract
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Background and Objectives: The mucous blanket as a smooth layer riding on the top of cilia in the respiratory mucosa provides the airway fluidity and protection from exogenous materials. However, the depth of the periciliary fluid layer is
critical for the interaction between the cilia and mucus as decreased depth of the periciliary fluid layer could disturb the mucociliary transport. The purpose of this study is to investigate the ultrastructural changes of mucous blanket in the
inflammatory mucosa of posterior ethmoid. Materials and Methods: We evaluated the ultrastructural changes of ethmoid mucous blanket using the transmission electron microscope (5 normal posterior ethmoid sinus mucosa and 5 posterior
ethmoiditis
mucosa). Results: Normal ethmoid maintained two layers of mucous blanket, but the mucous blanket from posterior ethmoiditis showed decreased periciliary fluid layer and increased mucous layer. Conclusion: Decreased periciliary fluid
layer
due to increased mucous layer in posterior ethmoiditis cause inactive ciliary beat and therefore can impair mucociliary transport. On the other hand, early drainage of mucus secretion in posterior ethmoiditis may improve the mucociliary
transport.
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